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Project title: Investigating the consequences of presynaptic interactions for basal ganglia function

Primary supervisor: Dr Enrico Bracci

Co-supervisor/s: Professor Paul Overton

Project description: We have recently discovered that neurons in the striatum (a nucleus important for motor control and reward processing) interact not only through conventional synapses but also through modulation of “third party” inputs. This project will explore the functional consequences of these interactions using a combination of electrophysiological, pharmacological and computational techniques.

Formal enquiries should be addressed to: Dr Enrico Bracci or Professor Paul Overton (p.g.overton@sheffield.ac.uk)

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