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Project title: Mathematical Modelling of Neurovascular function

Primary supervisor: Dr Jason Berwick

Project description: Developing and refining brain tissue models to enable world leading research into neurovascular coupling in health and disease. We are seeking highly skilled and motivated mathematical and/or programming postgraduate students to join our neurovascular research team that is investigating how the brain regulates its blood supply in health but also in diseases such as Alzheimer’s. The main focus of this project will be using theoretical methods such as Monte Carlos simulations to generate physiologically plausible models of how light penetrates brain tissue particularly how it is scattered and absorbed. The project will also refine the use of optogenetics that can be used to drive cells of the neurovascular unit with light.



Formal enquiries should be addressed to: Dr Jason Berwick (j.berwick@sheffield.ac.uk)

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